I've been thinking about getting started with Comfortis. We're looking for more information. I don't think that Comfortis users should panic, but if your dog needed to take extremely high doses of ivermectin (as in being treated for demodectic mange, not as in Heartgard-30), extreme caution is indicated. Here's a news release:
Rockville, Md. — Dogs receiving the drug Comfortis (spinosad) concurrently with high, extra-label doses of ivermectin are having adverse reactions in some cases, the Food and Drug Administration's Center for Veterinary Medicine (CVM) announced today.
The regulatory agency warns that it's received adverse reaction reports that are consistent with ivermectin toxicity. CVM advises veterinarians to not prescribe the two drugs concurrently for canine patients.
The safety warning also comes from Elanco Animal Health, which manufactures Comfortis, a monthly oral, chewable tablet used for the prevention and treatment of flea infestations on dogs. The company is addressing the issue, CVM officials say. Visit http://elms.xh1.lilly.com/10788_03_tech_Bulletin.pdf for more information.
|Date Published: June 24, 2008